A NOVAL TRANSDERMAL DRUG DELIVERY SYSTEM AND ITS POSSIBLE EVALUTATION: A REVIEW
Keywords:
TDDS, Bioavability, Iontophoresis, Electroporation, Sonophoresis, MicroneedlesAbstract
A transdermal patch is a medicated adhesive patch that is placed on the skin to deliver a specific dose of medication through the skin and into the bloodstream. The human skin is a readily accessible surface for drug delivery because it is one of the most readily accessible organs of the human body. There are many advantage of a transdermal drug delivery route over other types of medication delivery such as oral, topical, intravenous, intramuscular, etc. During the past three decade, there are number of drugs formulated in the patches formulation has hardly increased, and there has been little change in the composition of the patch systems. Modifications have been mostly limited to refinements of the materials used. The aim of this article reviews the selection of drug moiety, polymer, and method for which the patch to be formulated and followed by its possible evaluations.
Keywords: TDDS, Bioavability, Iontophoresis, Electroporation , Sonophoresis, Microneedles