Background: Drug used to treat bacterial infections. Antibiotics have no effect on viral infections. Originally, an antibiotic was a substance produced by one microorganism that selectively inhibits the growth of another. Synthetic antibiotics, usually chemically related to natural antibiotics, have since been produced that accomplish comparable tasks.
Method: The study was a prospective observational study and conducted at a tertiary care hospital. Collected the case of the patients treated with antibiotics for postoperative patients. Analyzing the prescription and categorizing it into varieties based on antibiotics prescribed, route of administration and the prescriptin pattern.
Result. The duration of therapy with antibiotics was ranging from one day,three days and five days). It was found that the highest number was prescribed with cefuroxime (1.5mg) and piperacillin/tazobactam(4.5mg), and in combination with piperacillin/tazobactam and Amikacin(4.5gm+750mg).
Conclusion: The most commonly prescribed antibiotics in the postoperative inÂpatients were found to be the cefuroxime followed by piperacillin/tazobactam and in combination of piperacillin/tazobactam and Amikacin. The use of these drugs seems to be effective in reducing the surgical site infection and other complications. There were no significant differences in prescribing the antibiotic with respect to age, gender, comorbid, height, weight and different surgeries.