Journal of Drug Discovery and Therapeutics http://jddt.in/index.php/jddt <p><span style="font-family: lucida sans unicode,lucida grande,sans-serif;"><span style="font-size: 14px;"><span style="text-align: justify;"><strong>Journal of Drug Discovery and Therapeutics (JDDT)</strong> is an international, peer-reviewed, open access, online journal dedicated to the rapid publication of full-length original research papers, short communications, invited reviews, Case studies and editorial commentary and news, Opinions &amp; Perspectives and Book Reviews written at the invitation of the Editor in all areas of the Biomedical and Pharmaceutical Sciences.</span></span></span></p> <p style="text-align: justify;"><span style="font-family: lucida sans unicode,lucida grande,sans-serif;"><span style="font-size: 14px;"><strong>Medical || Dentistry || Biomedical Sciences || Ayurveda || Homeopathy || </strong></span></span></p> <p style="text-align: justify;"><span style="font-family: lucida sans unicode,lucida grande,sans-serif;"><span style="font-size: 14px;">Anatomy, Physiology, Biochemistry, Molecular Biology, Cell biology, Genetics, Hematology, Pathology, Immunology, Microbiology, Virology, Parasitology, Surgery, Dental Sciences, Sports Physiology, Histopathology, Toxicology and all major disciplines of Biomedical Sciences.<br /><strong>Pharmaceutical Sciences || Allied Sciences </strong></span></span></p> <p style="text-align: justify;"><span style="font-family: lucida sans unicode,lucida grande,sans-serif;"><span style="font-size: 14px;">Pharmaceutics, Biopharmaceutics, Pharmacokinetics, Pharmaceutical/Medicinal Chemistry, Computational Chemistry and Molecular Drug Design, Pharmacognosy and Phytochemistry, Pharmacology and Toxicology, Pharmaceutical and Biomedical Analysis, Clinical Research, Pharmacy Practice, Clinical and Hospital Pharmacy, Cell Biology, Genomics and Proteomics, Pharmacogenomics, Bioinformatics and Biotechnology and all major disciplines of Pharmaceutical Sciences.</span></span></p> <p style="text-align: justify;"><span style="font-family: lucida sans unicode,lucida grande,sans-serif;"><span style="font-size: 14px;">Articles are published as they are accepted and are freely available on the journal’s website to facilitate rapid and broad dissemination of research findings to a global audience.</span></span></p> <p style="text-align: justify;"><span style="font-family: lucida sans unicode,lucida grande,sans-serif;"><span style="font-size: 14px;"><strong>Top Reasons for publication with us</strong></span></span></p> <p style="text-align: justify;"><span style="font-family: lucida sans unicode,lucida grande,sans-serif;"><span style="font-size: 14px;"><strong>Quick Quality Review:</strong> The journal has strong international team of editors and reviewers, Rapid Decision and Publication</span></span></p> <p style="text-align: justify;"><span style="font-family: lucida sans unicode,lucida grande,sans-serif;"><span style="font-size: 14px;"><strong>Very Low Publication Fees:</strong> Comparable journals charge a huge sum for each accepted manuscript. JDDT only charge the fees necessary to recoup cost associated with running the journal</span></span></p> <p style="text-align: justify;"><span style="font-family: lucida sans unicode,lucida grande,sans-serif;"><span style="font-size: 14px;"><strong>Other features:</strong> DIDS Assigned and Implemented the Open Review System (ORS).</span></span></p> <p style="text-align: justify;"><span style="font-family: lucida sans unicode,lucida grande,sans-serif;"><span style="font-size: 14px;"><strong>Important Notice:</strong></span></span></p> <p style="text-align: justify;"><span style="font-family: lucida sans unicode,lucida grande,sans-serif;"><span style="font-size: 14px;">Author can now directly send their manuscript as an email attachment to</span></span></p> <p style="text-align: justify;"><span style="font-family: lucida sans unicode,lucida grande,sans-serif;"><span style="font-size: 14px;">Innovative Library</span></span></p> <p style="text-align: justify;"><span style="font-family: lucida sans unicode,lucida grande,sans-serif;"><span style="font-size: 14px;"><strong>editor@jddt.in</strong>, <strong>editorjddt.in@gmail.com</strong></span></span></p> <p> </p> en-US editor@jddt.in (JDDT-PUBLISHER) INNOVATIVELIBRARY6@GMAIL.COM (INN. LIB) Thu, 19 Aug 2021 10:46:52 -0400 OJS 3.2.1.1 http://blogs.law.harvard.edu/tech/rss 60 Types of Knee Function Estimating Patient Reported Outcome Measures: A Review http://jddt.in/index.php/jddt/article/view/381 <p>Contribution of a patient’s insight about their health situation aids in revamping the treatments. Patient-reported outcome measures or PROMs gauge a patient’s point of view through questionnaires. The knee joint, being a more liable human part to suffer an injury, had been considered well by clinicians all around. There had been the introduction of numerous knee function measuring tools that could be either patient or clinician-administered. This article focuses on six patient-relevant outcome measures that are being used in various clinical as well as research contexts. This includes the IKDC Rating Scale, Oxford Knee Score, Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC), Knee Osteoarthritis Outcome Score (KOOS), Knee Outcome Survey- Activities of Daily Living (KOS-ADL) Scale and MARX Activity Rating Scale (MARS).</p> <p><strong>Keywords</strong>: Patient-reported outcome measures (PROMs), knee injury, IKDC, WOMAC, KOOS, questionnaires, KOOS-ADL, MARS</p> Julia Wilson, Alfet Raju Anthraper, K Krishnakumar Copyright (c) 2021 Journal of Drug Discovery and Therapeutics http://jddt.in/index.php/jddt/article/view/381 Thu, 19 Aug 2021 00:00:00 -0400 Agglomeration of Antihypertensive Drug by Spherical Crystallization Method http://jddt.in/index.php/jddt/article/view/392 <p>Hypertension is a key adaptable cardiovascular risk factor. There are several types of drugs that can be used in the management of hypertension. But the perfect treatment strategy remains uncertain for such a common and treatable disease. Various approaches applied for solubility and bioavailability improvement of poorly water-soluble drugs solid dispersion is one of the most successful method for increasing the drug dissolution rate of the drug. Although these techniques have commonly been used to increase dissolution rate of the drug, there are practical limitations with these techniques, the desired bioavailability enhancement may not always be achieved. In the current work, it was concentrated on improvement of the solubility of candesartan drug by spherical crystallization method. Findings were concluded that spherical agglomerates of candesartan prepared using spherical crystallization technique, showed significant improvement in flowability, compatibility, solubility and dissolution rate of the candesartan compared with pure candesartan.</p> <p><strong>Keywords:</strong> Hypertension, Candesartan, Spherical</p> Anand Patel, Vivek Patel, Pratyush Jain, Alok Pal Jain Copyright (c) 2021 http://jddt.in/index.php/jddt/article/view/392 Tue, 31 Aug 2021 00:00:00 -0400