A review on pathophysiology and treatment of aplastic anaemia

Abstract

Aplastic anaemia is a medical condition in which the bone marrow is fails to make enough blood cells such as RBC, WBC & Platelets. It is mostly 2 types such as acquired and inherited and it is caused by exposure to chemicals (benzene and some carbmates), radiation (U.V), Drugs (Choramphenicol, carbamezepines etc), infection (virus) and immune disease. In aplastic anaemia diagnosis can be confirmed by bone marrow examination and it can be   treated by immunosuppressive therapy, marrow stimulating agents and if aplastic anaemia is severe so used bone marrow transplantation.