EFFECT OF THIAZIDE AND LOOP DIURETICS ON SERUM MAGNESIUM AND OTHER ELECTROLYTES IN CARDIAC PATIENTS

Authors

  • Mathew George Department of Pharmacology, Pushpagiri College of Pharmacy,Thiruvalla, Kerala.

Abstract

Diuretics are agents that promote diuresis and are widely used for various indications like hypertension, edema of cardiac, renal failure or liver cirrhosis, acute pulmonary edema. Despite its key role, diuretics can have serious side effects like volume depletion and electrolyte disorders, with greater relevance in ageing population. Thiazide and loop diuretics have shown to cause alterations in serum magnesium and other electrolyte levels resulting in fatal complications like ventricular arrhythmias, coronary artery vasospasm or sudden death. This severely affects the quality of life of the patient especially those with cardiac illness. By this study we aim at reinforcing the importance of magnesium supplementation and the importance of including serum magnesium among the frequently monitored parameters, in the cardiac department.

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Published

2017-08-30

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Articles