DRUG EXCIPIENT COMAPATIBILITY STUDIES FOR MESALAMINE NANOSPEHERE FORMULATION

Authors

  • Tejas Pachpute Sunrise University, Alwar Pharmacy College, Alwar, Rajasthan, India.

Keywords:

Nanospheres, Mesalamine, FT-IR, Compatibilities, Eudragit R and S

Abstract

Abstract:
Drug and excipient compatibility is first step of pre-formulation studies for choose the best excipient for better and suitable formulation, this research article proposed that by the use of FT-IR checked the compatibility of drug with excipients, and finally concluded that that there was no significant Drug- Excipients interaction was observed. The results of FTIR study shown that there is no change in drug’s melting peak after the preparation of tablet. So we can conclude that drug and other excipients are compatible which each other.
Key words: Nanospheres, Mesalamine, FT-IR, Compatibilities, Eudragit R and S.

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Published

2018-03-30

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Section

Articles