An Overview on Classification, Mechanism of Extended Release Drug Delivery of Oral Formulations
ER is defined as a dosage form designed to release the medication in a controlled manner during an extended period of time, at a predetermined rate, duration, and location following administration. At steady state, the rate of absorption is approximately equivalent to the rate of elimination due to metabolism and excretion. ER (extended release) tablets shows the better patient compliance through reduction of frequency of dose administration and also maintain the therapeutic concentration over a long period of time it help to reduce the side effect of the drug and shows better effect. The ER tablet is very helpful to treat the chronic diseases. The objectives of this review are to discuss their advantages, classification and mechanism of extended drug release systems.