DEVELOPMENT OF A NOVEL HERBAL ANTIACNE FORMULATION: A REVIEW

Abstract

Acne is a pleomorphic condition of the skin that affects the pilosebaceous unit. It is characterized by lesions that are either noninflammatory (comedones, open and closed) or inflammatory (papules, pustules, and nodules). The prevalent pus-forming bacteria Propionibacterium acnes and Staphylococcus epidermidis cause different types of acne. Prolonged use of antibiotics, comedolytic medicines, and anti-inflammatory drugs—all of which have a history of side effects is a part of acne therapy. Furthermore, the extensive and prolonged use of antibiotics throughout time has regrettably resulted in the evolution of resistant strains and unfavorable side effects include erythema, dryness, scaling, burning, and itching, as well as hypersensitivity reactions that can harm the kidneys, liver, and lungs. Traditional or herbal formulas are preferred to prevent such obstacles. Herbs are effective, safe, and have many uses. The use of bioactive phytochemicals from a variety of botanicals functions not only as care taker of body and its parts but also the ingredients present therein influence biological functions of skin and provide nutrients necessary for the healthy skin. In general, botanicals provide different vitamins, antioxidants, various oils, essential oils, hydrocolloids, proteins, terpenoids and other bioactive molecules that can aid in the treatment of acne. Indian traditional systems of medicines, Ayurveda; Siddha; Unani and Tibetan system of medicine are of great help to identify the phytochemicals for skin and body care preparations.

KEYWORDS: Anti acne, Nanogel, Rose, Turmeric, Tulsi, Garlic, Aloe vera