A Comprehensive Analysis of Commercially Available Polyherbal Antiulcer Formulations

Abstract

Peptic ulcers occur when there is an imbalance between the protective and aggressive elements in the gastrointestinal system. The use of allopathic medications is common in modern ulcer treatment prescriptions. However, the search for new, safer drugs has been prompted by a number of drawbacks, including side effects, discordance, and changed physiological characteristics. Ayurveda has a long history of using herbal remedies to cure ulcers. Several benefits, such as synergistically enhanced positive effects, improved patient compliance, and reduced dosage of individual medications without compromising therapeutic effects, are shown by combining such herbs, which is called polyherbal formulation. Improved Ayurvedic medicine has been used in treatment settings in recent years thanks to this priceless traditional knowledge of the therapeutic properties of plants and modern value-added innovations. Over the last 20 years, several polyherbal combinations have been researched and tested for their ability to alleviate ulcer symptoms. Thanks to developments in analytical technologies, phytoconstituents from crude herbal medications have been isolated and examined for their therapeutic advantages. The primary objective of this study is to provide a thorough synopsis of the ingredients used in various polyherbal formulations sold as antiulcer medications, as well as an analysis of the preclinical models used to demonstrate the gastroprotective effects of these products.

Keywords: Antiulcer, Ulcer, Phytoconstituents, and Polyherbal formulations