Review on Anti-HIV Drugs

Authors

  • Shubhangi Eknath Sawant Research Scholars, Department of Pharmacy, Sabarmati University, Ahmedabad, Gujrat
  • Vivek Subhash Tarate Supervisor & Professor, Department of Pharmacy, Sabarmati University, Ahmedabad, Gujrat
  • Jagadishchandra Pati Co-Supervisor & Professor, Department of Pharmacy, Sabarmati University, Ahmedabad, Gujrat

Keywords:

HIV

Abstract

Human Immunodeficiency Virus (HIV) infection remains a major global health challenge. Antiretroviral therapy (ART) has significantly improved the survival and quality of life of people living with HIV by suppressing viral replication and preventing disease progression. Among the most widely used antiretroviral agents are Efavirenz, a non-nucleoside reverse transcriptase inhibitor (NNRTI), and Tenofovir, a nucleotide reverse transcriptase inhibitor (NRTI). These drugs are frequently used in combination with other antiretroviral agents as first-line therapy. This review discusses their pharmacology, mechanism of action, pharmacokinetics, clinical uses, adverse effects, drug interactions, and recent advances.

Keywords: HIV, Antiretroviral therapy, Efavirenz, Tenofovir, Reverse transcriptase inhibitors, AIDS.

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Published

2024-12-30

Issue

Vol. 12 No. 6 (2024)

Section

Articles