DERMAL TRANSPORT OF MACRO-MOLECULE MEDICINES

Authors

  • Pramod Singh Khatri PhD. Scholar, Department of Pediatrics, AIIMS Hospital, India.

Abstract

These delivery techniques may be perfect; they do have numerous weaknesses when contrasted with infusions. For instance, oral administration requires proficient assimilation through the gastrointestinal (GI) tract. In this manner, a pill must be impervious to the savage physicochemical environment put forth in both the stomach and the intestines.

The oral delivery of pills likewise exposes them to first-pass metabolism inside the liver; this regularly brings about essentially diminished bioavailability; that is, the rate at which the active pill enters the systemic flow.

 

KEYWORDS: Biphasic vesicles, pills, macromolecules medicine

 

Published

2013-06-30

Issue

Vol. 1 No. 6 (2013)

Section

Articles